ANC Formula:
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The Absolute Neutrophil Count (ANC) is a measure of the number of neutrophil granulocytes (a type of white blood cell) present in the blood. It's an important indicator of immune system function and infection risk.
The calculator uses the ANC formula:
Where:
Explanation: The formula calculates the absolute number of neutrophils by multiplying the total white blood cell count by the percentage of neutrophils.
Details: ANC is crucial for assessing infection risk, especially in chemotherapy patients. It helps determine neutropenia severity and guides treatment decisions.
Tips: Enter WBC count in cells/μL and neutrophil percentage from differential count. Both values must be positive numbers (neutrophil % between 0-100).
Q1: What is a normal ANC range?
A: Normal range is typically 1,500-8,000 cells/μL. Below 1,500 is neutropenia, and below 500 is severe neutropenia.
Q2: Why is ANC important for chemotherapy?
A: Chemotherapy often causes neutropenia. Monitoring ANC helps determine infection risk and need for growth factor support.
Q3: What are bands in ANC calculation?
A: Some protocols include band neutrophils (immature neutrophils) in the ANC calculation for more sensitive monitoring.
Q4: How often should ANC be checked?
A: Frequency depends on clinical situation - daily for hospitalized patients, weekly for chemotherapy patients.
Q5: Can ANC predict infection risk?
A: Yes, lower ANC correlates with higher infection risk, especially for bacterial and fungal infections.